![]() It wasn’t just about doing the right thing you had to do it the right way. Reid, MD, former director of the National Heart, Lung, and Blood Institute’s Sickle Cell Disease Program, can still recall “the shock effect” of his words. To improve understanding of test results, he called for more education and counseling.Ĭlarice D. Recently named director of the University’s laboratories, he assailed crude testing practices. ![]() In journal articles and meetings with lead players, Bowman excoriated the conflation of sickle cell anemia with the more common sickle cell trait (in which just one predisposing gene, as opposed to the two needed to produce the disease, is present, and the person is healthy) that was fanning public alarm. Bowman, MD, who died in September 2011 at 88, had just become the first tenured African American faculty member in medicine at the University. ![]() And in the well-intentioned zeal to roll out mass testing and raise awareness, little attention was being paid to the accuracy of information disseminated to the public and the ethical implications of screening on the scale that was being embraced, said an outspoken professor of medicine and pathology from the University of Chicago. The following year, he signed the National Sickle Cell Anemia Control Act, which authorized funding for screening, outreach and research to “reverse the record of neglect on this dread disease.”Īfter decades of inaction, there was a headlong rush to tackle sickle cell anemia. In February 1971, President Richard Nixon designated sickle cell anemia one of two critical areas for urgent investment under his proposed “National Health Strategy.” The other was cancer. On the streets, the Black Panther Party took matters into its own hands, utilizing a newly available testing kit to mobilize screening in African American communities, including in Chicago. Yet funding was a fraction of that for less prevalent disorders afflicting other groups, the author wrote. Roughly one in 500 African Americans was born with the condition, noted an article in the Journal of the American Medical Association that October. For patients, life expectancy was about 20 years. The second part is joint work with Ke Ye.In 1970, there was no treatment for the blood disorder sickle cell anemia, and knowledge of how to manage it was rudimentary. Our method is a generalization of the Cohn-Umans method, allowing for arbitrary bilinear operations in place of matrix-matrix product, and arbitrary algebras (e.g., coordinate rings of schemes, cohomology rings of manifolds, PI algebras) in place of group algebras. As an explicit example, we determine the fastest algorithms for the basic operation underlying Krylov subspace methods - the structured matrix-vector products for sparse, banded, triangular, symmetric, circulant, Toeplitz, Hankel, Toeplitz-plus-Hankel, BTTB matrices - by analyzing their structure tensors. In matrix computations, a decomposition of the structure tensor into rank-1 terms gives an explicit algorithm for solving the problem, its tensor rank gives the speed of the fastest possible algorithm, and its nuclear norm gives the numerical stability of the stablest algorithm. For example, the Grothendieck constant, which plays an important role in unique games conjecture and SDP relaxations of NP-hard problems, arises as the spectral norm of such a structure tensor. July 18, 11:30 ~ 12:30 Structure Tensors Lek-Heng Lim University of Chicago, USA - show that in many instances, at the heart of a problem in numerical computation sits a special 3-tensor, the structure tensor of the problem that uniquely determines its underlying algebraic structure.
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